List of Publications
1994 - 1998
The original articles included in the CMRC list of publications are selected according to the following criteria:
In addition, more important published lectures, chapters in book and reviews summarizing CMRC research are also listed. No abstracts have been included.
Of the articles on the list, those published 1994 and some 1995 are based on experimental work performed before the establishment of the CMRC.
Three senior CMRC researchers (Bente Klarlund Pedersen, Bjørn Quistorff, and Niels H. Secher) have major research activities not directly related to CMRC projects. The articles and doctoral theses from these distinct research fields are not included in the publication list.
I. Skeletal Muscle
Growth and Differentiation
Theses
Defended
Ph.D. thesis: Jesper L. Andersen. Changes in myosin heavy chain expression due to training and detraining. Faculty of Science, University of Copenhagen.Defended March, 1997.
Original articles
1994
Andersen JL, Klitgaard H, Bangsbo J, Saltin B. Myosin heavy chain isoforms in single fibres from m. Vastus lateralis of soccer players: effects of strength-training. Acta Physiol Scand 150, 21-26, 1994.
Andersen JL, Klitgaard H, Saltin B. Myosin heavy chain isoforms in single fibres from m. Vastus lateralis of sprinters: influence of training. Acta Physiol Scand 151, 135-142, 1994.
1995
Edgerton VR, Zhou M-Y, Ohira Y, Klitgaard H, Jiang B, Bell G, Harris B, Saltin B, Gollnick PD, Roy RR, Day MK, Greenisen M. Human fiber size and enzymatic properties after 5 and 11 days of spaceflight. J Appl Physiol 78, 1733-1739, 1995.
Zhou M-Y, Klitgaard H, Saltin B, Roy RR, Edgerton VR, Gollnick PD. Myosin heavy chain isoforms of human muscle after short-term spaceflight. J Appl Physiol 78, 1740-1744, 1995.
1996
Andersen JL, Mohr T, Biering-Sørensen F, Galbo H, Kjær M. Myosin heavy chain isoform transformation in single fibres from m. vastus lateralis in spinal cord injured individuals: Effects of long-term functional electrical stimulation (FES). Pflügers Arch 431, 513-518. 1996.
Harridge SDR, Bottinelli R, Canepari M, Pellegrino MA, Reggiani C, Esbjörnsson M, Saltin B. Whole-muscle and single-fibre contractile properties and myosin heavy chain isoforms in humans. Pflügers Arch 432, 913-920. 1996.
1997
Andersen JL, Schiaffino S. Mismatch between myosin heavy chain mRNA and protein distribution in human skeletal muscle fibers. Am J Physiol 272, C1881-1889, 1997.
Harridge SDR, Magnusson G, Saltin B. Life-long endurance-trained elderly men have high aerobic power, but have similar muscle strength to non-active elderly men. Aging Clin Exp Res 9, 80-87, 1997.
Mohr T, Andersen JL, Biering-Sørensen F, Galbo H, Bangsbo J, Wagner Å, Kjær M. Long term adaptation to electrically induced cycle training in severe spinal cord injured individuals. Spinal Cord 35, 1-16, 1997.
Mohr T, Pødenphant J, Biering-Sørensen F, Galbo H, Thamsborg G, Kjær M. Increased bone mineral density after prolonged electrically induced cycle training of paralyzed limbs in spinal cord injured man. Calcified Tissue Int 61, 22-25, 1997.
Qu Z, Andersen JL, Zhou S. Visualization of capillaries in human skeletal muscle. J Histochem 107, 169-174, 1997.
Sullivan MJ, Duscha BD, Klitgaard H, Kraus WE, Cobb FR, Saltin B. Altered expression of myosin heavy chain in human skeletal muscle in chronic heart failure. Med Sci Sports Exerc 29, 860-866, 1997.
1998
Aagaard P, Andersen JL. Correlation between contractile strength and myosin heavy chain isoform composition in human skeletal muscle. Med Sci Sports Exerc 30, 1217-1222, 1998.
Daugaard JR, Lausten JL, Hansen BS, Richter EA. Growth hormone induces muscle fibre type transformation in growth hormone-deficient rats. Acta Physiol Scand 164, 119-126, 1998.
Harridge SDR, Bottinelli R, Canepari M, Pellegrino MA, Reggiani C, Esbjörnsson M, Balsom, PD, Saltin B. Sprint training, in vitro and in vivo muscle function, and myosin heavy chain expression. J Appl Physiol 84, 442-449, 1998.
Vissing J, Salamon MB, Arlien-Søborg P, Nørby S, Manta P, DiMauro S, Schmalbruch H. A new mitochondrial tRNAMet gene mutaion in a patient with dystrophic muscle and exercise intolerance. Neurology 50, 1875-1878, 1998.
Book Chapters, Symposia Contributions, etc.
1996
Bonde-Petersen F, Andersen JL, Saltin B. Muscle morphological characteristics with disuse; comparison of bed rest and space flights. ESA Symposium Proceedings on "Space Station Utilisation". ESOC, Darmstadt, Germany, December 1996.
Harridge SDR. The muscle contractile system and its adaptation to training. In: Human Muscular Function during Dynamic Exercise. Eds: Marconnet P, Saltin B, Komi P, Poortmans J. Med Sport Sci, Basel, Karger, 41, 82-94, 1996.
Harridge SDR, Saltin B. Neuromuscular system. In: Encyclopedia of Gerontology, vol. 2, 211-220, 1996.
Hartkopp A, Harridge SDR, Mizuno M, Ratkevicius A, Gregersen H, Hagen E, Kjær M, Quistorff B, Biering-Sørensen F. Preliminary results of muscle strength, endurance and metabolism in the wrist extensors of tetraplegics following 12 weeks of electrically induced training. In: Neuroprosthetics. From basis research to clinical application. Eds. Pedotti A, Ferrain M, Quintern J, Riener R. Springer Verlag, Berlin, 579-590, 1996.
II. Metabolism
II.a. Carbohydrate and lipid metabolism
Theses
Defended
Doctoral thesis: Dela F. On the influence of physical training on glucose homeostasis. Acta Physiol Scand 158 (suppl. 635), 5-41, 1996.
Ph.D. thesis: Helge, JW. Interaction of diet and training on endurance performance and substrate utilization". Faculty of Sciences, University of Copenhagen. Defended May 1997.
Ph.D. thesis: Kristiansen S. Translocation of glucose transporter (GLUT-4) proteins in rat and human skeletal muscle. August Krogh Institute, University of Copenhagen, 1996.
Ph.D. thesis: Linstow M. von. The effect of training on insulin secretion and metabolism in type 2 diabetics. Dept. of Medical Physiology, The Panum Institute, University of Copenhagen, 1998.
Ph.D. thesis: Mohr T. Long term adaptation to electrically induced cycle training in spinal cord injured individuales. Department of Medical Physiology. The Panum Institute, University of Copenhagen, 1996.
Ph.D. thesis: Stallknecht B. Estimation of interstitial concentrations of metabolites and hormones in adipose tissue by means of microdialysis - method evaluation. Department of Medical Physiology, The Panum Institute. University of Copenhagen. Defended May 1997.
Ph.D. thesis: Wojtaszewski J. Signal transduction in exercise- and insulin-stimulated glucose transport in skeletal muscle. Faculty of Science, University of Copenhagen. Defended December 1997.
Submitted
Doctoral thesis: Vissing J. Neural control mechanisms in the regulation of neuroendocrine activity, glucose homeostasis and circulation during exercise. Submitted to the Faculty of Health Sciences, University of Copenhagen, 1998.
Original articles
1994
Dela F, Mikines KJ, Sonne B, Galbo H. Effect of training on interaction between insulin and exercise in human muscle. J Appl Physiol 76, 2386-2396, 1994.
Dela F, Ploug T, Handberg Aa, Petersen LN, Larsen JJ, Mikines KJ, Galbo H. Physical training increases muscle GLUT4 protein and mRNA in patients with NIDDM. Diabetes 43, 862-865, 1994.
Dijk Gv, Vissing J, Steffens AB, Galbo H. Effect of anaesthetizing the region of the paraventricular hypothalmic nuclei on energy metabolism during exercise in the rat. Acta Physiol Scand 151, 165-172, 1994.
Eriksson KF, Saltin B, Lindgärde F. Increased skeletal muscle capillary density precedes diabetes development in men with impaired glucose tolerance: a fifteen year follow-up. Diabetes 43, 805-808, 1994.
Han X, Galbo H. The effect of putative insulin-like substances released by the motor nerve on glucose transport in perfused muscle. Acta Physiol Scand 151, 181-189, 1994.
Kjær M, Jurlander J, Keiding S, Galbo H, Kirkegaard P, Hage E. No reinnervation of hepatic sympathetic nerves after liver transplantation in humans. J Hepatol 20, 97-100, 1994.
Kristiansen S, Wojtaszewski J, Juel C, Richter EA. Effect of glucose-6-phosphate and pH on glucose transport in skeletal muscle plasma membrane giant vesicles. Acta Physiol Scand 150, 227-233, 1994.
Ralston E, Beushausen S, Ploug T. Expression of the synaptic vesicle proteins VAMPs/Synaptobrevins 1 and 2 in non-neural tissue. J Biol Chem 269, 15403-15406, 1994.
Turcotte LP, Hespel PJL, Graham, TE, Richter EA. Impaired plasma FFA oxidation imposed by extreme CHO deficiency in contracting rat skeletal muscle. J Appl Physiol 77, 517-525, 1994.
Vaag A, Handberg A, Skött P, Richter EA, Beck-Nielsen H. Glucose-fatty acid cycle operates in humans at the levels of both whole body and skeletal muscle during low and high physiological plasma insulin concentrations. Eur J Endocrinol 130, 70-79, 1994.
Vergauen L, Hespel P, Richter EA. Adenosine receptors mediate synergistic stimulation of glucose uptake and transport by insulin and by contractions in rat skeletal muscle. J Clin Invest 93, 974-981, 1994.
Vissing J, Iwamoto GA, Fuchs IE, Galbo H, Mitchell JH. Reflex control of glucoregulatory exercise responses by group III and IV muscle affereents. Am J Physiol 266, R824-R830, 1994.
1995
Asp S, Daugaard JR, Richter EA. Eccentric exercise decreases glucose transporter GLUT4 protein in human skeletal muscle. J Physiol 482, 705-712, 1995.
Asp S, Kristiansen S, Richter EA. Eccentric muscle damage transiently decreases rat skeletal muscle GLUT4 protein. J Appl Physiol 79, 1338-1345, 1995.
Dela F, Larsen JJ, Mikines KJ, Galbo H. Normal effect of insulin to stimulate leg blood flow in NIDDM. Diabetes 44, 221-226, 1995.
Dela F, Larsen JJ, Mikines KJ, Ploug T, Pedersen LN, Galbo H. Insulin-stimulated muscle glucose clearance in patients with NIDDM : effects on one-legged physical training. Diabetes 44, 1010-1020, 1995.
Han X, Handberg Aa, Petersen LN, Ploug T, Galbo H. Stability of GLUT-1 and GLUT-4 expression in perfused rat muscle stimulated by insulin and exercise. J Appl Physiol 78, 46-52, 1995.
Han X, Ploug T, Galbo H. Effect of diet on insulin and contraction mediated glucose transport and uptake in rat muscle. Am J Physiol 269, R544-R551, 1995.
Hespel P, Vergauen L, Vanderberghe K, Richter EA. Important role of insulin and flow in stimulating glucose uptake in contracting skeletal muscle. Diabetes 44, 210-215, 1995.
Kim CK, Bangsbo J, Strange S, Karpakka J, Saltin B. Metabolic response and muscle glycogen depletion pattern during prolonged electrically induced dynamic exercise in man. Scand J Rehab Med 27, 51-58, 1995.
Kjær M, Keiding S, Engfred K, Rasmussen K, Sonne B, Kirkegård P, Galbo H. Glucose homeostasis during exercise in humans with a liver or kidney transplant. Am J Physiol 268, E636-E644, 1995.
Linstow M, Mikines KJ, Dela F, Galbo H. Paradoxical inhibition of insulin secretion by glucose in non-insulin dependent diabetic patients. Acta Diabetol 32, 1-6, 1995.
Ploug T, Ohkuwa T, Handberg Aa, Vissing J, Galbo H. Effect of immobilization on glucose transport and glucose transporter expression in rat skeletal muscle. Am J Physiol 268, E980-E986, 1995.
Stallknecht B, Simonsen L, Bülow J, Vinten J, Galbo H. Effect of training on epinephrine-stimulated lipolysis determined by microdialysis in human adipose tissue. Am J Physiol 269, E1059-E1066, 1995.
Turcotte LP, Hespel PL, Richter EA. Circulating palmitate uptake and oxidation are not altered by glycogen depletion in contracting perfused skeletal muscle. J Appl Physiol 78, 1266-1272, 1995.
Vandenberghe K, Hespel P,Van den Eynde B, Lysens R, Richter EA. No effect of glycogen level on glycogen metabolism during high intensity exercise. Med Sci Sports Exerc 27, 1278-1283, 1995.
Wiersma MML, Vissing J, Mikines KJ, Steffens AB, Galbo H. Effect of liver denervation on glucose production during running i guinea pigs. Am J Physiol 268, R72-R77, 1995.
1996
Asp S, Daugaard JR, Kristiansen S, Kiens B, Richter EA. Eccentric exercise decreases maximal insulin action in humans: muscle and systemic effects. J Physiol 494, 891-898, 1996.
Asp S, Richter EA. Decreased insulin action on muscle glucose transport after eccentric contractions in rats. J Appl Physiol 81, 1924-1928, 1996.
Dela F, Mikines KJ, Larsen JJ, Galbo H. Training induced enhancement of insulin action in human skeletal muscle. The influence of ageing. J Gerontology 51, B247-B252, 1996.
Hall Gv, MacLean DA, Saltin B, Wagenmakers AJM. Mechanisms of activation of muscle branched-chaina-keto acid dehydrogenase during exercise in man. J Physiol 494, 899-905, 1996.
Helge JW, Richter EA, Kiens B. Interaction of training and diet on metabolism and endurance during exercise in man. J Physiol 492, 293-306, 1996.
Kiens B, Richter EA. Types of carbohydrate in an ordinary diet affect insulin action and muscle substrates in humans. Am J Clin Nutr. 1996, 63, 47-53, 1996.
Kjær M, Pollack SF, Mohr T, Weiss H, Gleim GW, Bach FW, Nicolaisen T, Galbo H, Ragnarsson KT. Regulation of glucose turnover and hormonal responses during electrical cycling in tetraplegic humans. Am J Physiol 271, R191-R199, 1996.
Kjær M, Secher NH, Bangsbo J, Perko G, Horn A, Mohr T, Galbo H. Hormonal and metabolic responses to electrically induced cycling during epidural anesthesia in humans. J Appl Physiol 80, 2156-2162, 1996.
Kristiansen S, Asp S, Richter EA. Decreased muscle GLUT-4 and contraction-induced glucose transport after eccentric contractions. Am J Physiol 271, R477-R482, 1996.
Kristiansen S, Hargreaves M, Richter EA. Exercise-induced increase in glucose transport, GLUT-4 and VAMP-2 in plasma membrane from human muscle. Am J Physiol 270, E197-E201, 1996.
Kristiansen S, Youn J, Richter EA. Effect of vanadate on glucose transporter (GLUT4) intrinsic activity in skeletal muscle plasma membrane giant vesicles. Biochem Biophys Acta 1282, 71-75, 1996.
Madsen K, MacLean DA, Kiens B, Christensen D. Effect of oral glucose and branched chain amino acids on exercise performance in trained cyclists. J Appl Physiol 81, 2644-2640, 1996.
Ralston E, Ploug T. GLUT4, in cultured myotubes, is segregated from the transferrin receptor and stored in vesicles associated with the Golgi complex. J Cell Science 109, 2967-2978, 1996.
Stallknecht B, Roesdahl M, Vinten J, Capito K, Galbo H. The effect of lesions of the sympathoadrenal system on training induced adaptations in adipocytes and pancreatic islets in rats. Acta Physiol Scand 156, 465-473, 1996.
Tanner VA, Ploug T, Tao-Cheng J-H. Subcellular localization of SV2 and other secretory vesicle components in PC12 cells by an efficient method of preembedding EM immunocytochemistry for cell cultures. J Histochem Cytochem 44, 1481-1488, 1996.
Van Soeren M, Mohr T, Kjær M. Graham T. Acute effects of caffeine ingestion at rest in humans with impaired epinephrine response. J Appl Physiol 80, 999-1005, 1996.
Vissing J, Galbo H, Haller RG. Exercise fuel mobilization in mitochondrial myopathy: a metabolic dilemma. Ann Neurol 40, 655-662, 1996.
Vissing J, Galbo H, Haller RG. Paradoxically enhanced glucose production during exercise in humans with blocked glycolysis due to muscle phosphofructokinase deficiency. Neurology 47, 766-771, 1996.
Wojtaszewski JFP, Hansen BF, Ursø B, Richter EA. Wortmannin inhibits both insulin- and contraction-stimulated glucose uptake and transport in rat skeletal muscle. J Appl Physiol 81, 1501-1509, 1996.
Ørskov J, Bak JF, Abildgård N, Schmitz O, Andreasen F, Richter EA, Skjærbæk C, Møller N. Inhibition of muscle glycogen synthase activity and non-oxidative glucose disposal during hypoglycaemia in normal man. Diabetologica, 39, 226-234, 1996.
1997
Asp S, Rohde T, Richter EA. Impaired muscle glycogen resynthesis after a competetive race is not caused by decreased muscle GLUT4 content. J Appl Physiol 83, 1482-1485, 1997.
Asp S, Watkinson A, Noakes ND, Kraegen EW. Prior eccentric contractions impair maximal insuling action on muscle glucose uptake in the conscious rat. J Appl Physiol 82, 1327-1332, 1997.
Bangsbo J, Madsen K, Kiens B, Richter EA. Muscle glycogen resynthesis in recovery from intense exercise in humans. Am J Physiol 273, E416-E424, 1997.
Calbet JAL, MacLean DA. Role of caloric content on gastric emptying in humans. J Physiol 498, 553-559, 1997.
Dyck DJ, Peters SJ, Glatz J, Gorski J, Keizer H, Kiens B, Liu S, Richter EA, Spriet LL, Van der Vusse GJ, Bonen A. Functional differences in lipid metabolism in resting skeletal muscle of various fibre types. Am J Physiol 272, E340-E351, 1997.
Helge JW, Kiens B. Muscle enzyme activity in humans: role of substrate availability and training. Am J Physiol 272, R1620-R1624, 1997.
Kiens B, Kristiansen S, Jensen P, Richter EA, Turcotte LP. Membrane associated FABP in human skeletal muscle is increased by endurance training. Biochim Biophys Res Com 231, 463-465, 1997.
Kristiansen S, Darakhshan F, Richter EA, Hundal HS. Fructose transport and GLUT5 protein in human sarcolemmal vesicles. Am J Physiol 273, E543-E548, 1997.
Kristiansen S, Hargreaves M, Richter EA. Progressive increase in glucose transport and GLUT4 in human sarcolemmal vesicles during moderate exercise. Am J Physiol 272, E385-E389, 1997.
Kristiansen S, Jones J, Handberg A, Dohm L, Richter EA. Eccentric contractions decrease glucose transporter (GLUT4) transcription rate, mRNA and protein in skeletal muscle. Am J Physiol 272, C1734-C1738, 1997.
Larsen JJ, Dela F, Kjær M, Galbo H. The effect of moderate exercise on postprandial glucose homeostasis in NIDDM patients. Diabetologia 40, 447-453, 1997.
Larsen JJ, Hansen JM, Olsen NV, Galbo H, Dela F. The effect of altitude hypoxia on glucose homeostasis in men. J Physiol 504, 241-249, 1997.
Nyholm B, Qu Z, Kaal A, Pedersen SB, Gravholt HC, Andersen JL, Saltin B, Schmitz O. Evidence of an increased number of type IIb muscle fibres in insulin resistant first-degree relatives of patients with NIDDM. Diabetes 46, 1822-1828, 1997.
Ploug T, Han XX, Petersen LN, Galbo H. Effects of in vivo injection of cholera and pertussis toxin on glucose transport in rat skeletal muscle. Am J Physiol 272, E7-E17, 1997.
Stallknecht B, Bülow J, Frandsen E, Galbo H. Desensitization of human adipose tissue to adrenaline stimulation studied by microdialysis. J Physiol 500, 271-282, 1997.
Vergauwen L, Richter EA, Hespel PL. Adenosine exerts a glycogen-sparing action in contraction rat skeletal muscle. Am J Physiol 272, E762-E768, 1997.
Wojtaszewski JFP, Hansen BF, Kiens B, Richter EA. Insulin signaling in human skeletal muscle: time course and effect of exercise. Diabetes 46, 1775-1781, 1997.
1998
Aronson D, Wojtaszewski JFP, Thorell A, Nygren J, Zangen D, Richter EA, Ljungqvist O, Fielding RA, Goodyear LJ. Extracellular-regulated protein kinase cascades are activated in response to injury in human skeletal muscle. Am J Physiol 275, C555-C561, 1998.
Asp S, Daugaard JR, Kristiansen S, Kiens B, Richter EA. Exercise metabolism in human skeletal muscle exposed to prior eccentric exercise. J Physiol 509, 305-313, 1998.
Bonen A, Luiken JJFP, Liu S, Dyck DK, Kiens B, Kristiansen S, Turcotte LP, Van der Vusse GJ, Glatz JFC. Palmitate transport and fatty acid transporters in red and white muscles. Am J Physiol 275, E471-E478, 1998.
Darakhshan F, Hajduch E, Kristiansen S, Richter EA, Hundal HS. Biochemical and functional characterization of the GLUT5 fructose transporter in rat skeletal muscle. Biochem J 336, 361-366, 1998.
Helge JW, Ayre K, Chaunchaiyakul K, Hulbert AJ, Kiens B, Storlien LH. Endurance in high-fat-fed rats: effects of carbohydrate content and fatty acid profile. J Appl Physiol 85, 1342-1348, 1998.
Helge J, Wulff B, Kiens B. Impact of a fat-rich diet on endurance in man: role of the dietary period. Med Sci Sports Exerc 30(3), 456-461, 1998.
Kiens B, Richter EA. Utilization of muscle triacylglycerol during postexercise recovery in man. Am J Physiol 275, E332-E337, 1998.
Kristiansen K, Ramlal T, Klip A. Phosphatidylinositol 4-kinase, but not PI 3-kinase, is present in GLUT4-containing vesicles isolated from rat skeletal muscle. Biochem J 335, 351-356, 1998.
Mizuno M, Secher NH. Glycogen depletion and lactate accumulation in human intercostal muscles after administration of succinylcholine. Br J Anasth 80, 302-307, 1998.
Mohr T, Soeren Mv, Graham T, Kjær M. Improved exercise performance with caffeine during involuntary exercise in spinal cord injured man. J Appl Physiol 85, 979-985, 1998.
Ploug T, van Deurs B, Ai H, Cushman SW, Ralston E. Analysis of GLUT4 distribution in whole skeletal muscle fibers: identification of distinct storage compartments that are recruited by insulin and muscle contractions. J Cell Biol 142, 1429-1446, 1998.
Richter EA, Jensen P, Kiens B, Kristiansen S. Sarcolemmal glucose transport and GLUT4 translocation during exercise are diminished by endurance training. Am J Physiol 274, E89-E95, 1998.
Wojtaszewski JFP, Jakobsen AB, Ploug T, Richter EA. The perfused hindlimb is suitable for skeletal muscle glucose transport measurements. Am J Physiol 274, E184-E191, 1998.
Wojtaszewski JFP, Laustsen JL, Derave W, Richter EA. Hypoxia and contractions do not utilize the same signaling mechanism in stimulating skeletal muscle glucose transport. Biochim Biophys Acta 1380, 396-404, 1998.
Reviews, Book chapters, Symposia contributions, etc.
1994
Kjær M, Mohr T. Substrate mobilization, delivery and utilization in physical exercise - regulation by hormones in healthy and diseased humans. CRC, Critical Rev. In Physical and Rehabilitation Med 9, 1-16, 1994.
Richter EA, Sutton JR. Hormonal adaptation to physical activity. In: Physical Activity, Fitness, and Health. Eds: Bouchard C, Shepherd R, Stephens T. Champaign, Ill, USA, Human Kinetics, 331-342, 1994.
1995
Dela F, Ploug T, Handberg A, Petersen LN, Larsen JJ, Galbo H. The effect of physical training on skeletal muscle GLUT4 protein and mRNA content in NIDDM. In: Kawamori R, Vranic M, Horton ES, Kubota M (eds), Glucose fluxes, exercise and diabetes. Smith-Gordon, GB, pp 137-140, 1995.
Galbo H. Integrated endocrine responses and exercise. In: De Groot LJ (ed), Endocrinology, 3rd ed. WB Saunders Company, PA, pp 2692-2701, 1995.
Galbo H. Exercise protocols in diabetes. In: Mogensen CE, Standl E (eds), Research methodologies in human diabetes. Diabetes Forum Series, Vol. 5. Walter d. Gruyter, Berlin, pp 191-206, 1995.
Kjær M. Hepatic fuel metabolism during exercise. In: Hargreaves M (ed), Exercise Metabolism. Human Kinetics Publishers, pp 73-98, 1995.
Larsen JJS, Dela F, Sie M, Kjær M, Mikines KJ, Galbo H. The effect of exercise on postprandial glucose and insulin concentration in type II diabetic patients. In: Kawamori R, Vranic M, Horton ES, Kubota M (eds), Glucose fluxes, exercise and diabetes. Smith-Gordon, GB, pp 29-35, 1995.
Turcotte LP, Kiens B, Richter EA. Lipid metabolism during exercise. In: Exercise Metabolism. Ed: Hargreaves M. Human Kinetics Publishers, pp 99-130, 1995.
1996
Galbo H, Stallknecht B. Regulation of fat metabolism in exercise. In "Biochemistry of Exercise". Eds: Maughan RJ, Shirreffs SM. Champaign, Ill, USA, Human Kinetics, 63-71, 1996.
Hespel P, Vergauwen L, Vandenberghe K, Richter EA. Significance of insulin for glucose metabolism in skeletal muscle during contractions. Diabetes 45, S99-S104, 1996.
Kjær M, Fernandes A, Secher NH, Keiding S, Kirkegaard P, Beyer N, Galbo H. Sympathetic liver innervation and regulation of hepatic glucose production during exercise - human experiments with pharmacological blockade and liver denervation. In: Liver Innervation. Ed: Shimazu T. John Libbey Co., 465-469, 1996.
Mohr T, Christensen PT, Biering-Sørensen F, Pødenphant J, Andersen JL, Wagner Å, Galbo H, Kjær M. Long-term electrically induced bicycling in spinal cord injured. A pilot study. In: Neuroproshetics - from basic research to clinical application. Eds.: Pedotti A. 579-590, 1996.
Richter EA. Glucose utilization. In: Handbook of Physiology, XII. Exercise: Regulation and integration of multiple systems. Eds: Rowell LB, Shepherd JT. New York, Oxford Univ. Press, 912-951, 1996.
Richter EA, Hespel P. Determinants of glucose uptake in contracting muscle. In: Biochemistry of Exercise, eds. Maugham RJ, Shirreffs SM. Champaign, Ill., USA. Human Kinetics, p. 51-60, 1996.
Richter EA, Kiens B, Turcotte L. Transport and metabolism of FFA in muscle. In: Biochemistry of Exercise. Eds. Maughan RJ, Shirreffs SM. Human Kinetics, Champaign, Ill, pp 97-104, 1996.
1997
Hayashi T, Wojtaszewski JFP, Goodyear LJ. Exercise regulation of glucose transport in skeletal muscle. Am J Physiol 273, E1039-E1051, 1997.
Kiens B. Effect of endurance training on fatty acid metabolism: local adaptations. Med Sci Sports Exerc 29, 640-645, 1997.
1998
Cushman SW, Goodyear LJ, Pilch PF, Ralston E, Galbo H, Ploug T, Kristiansen S, Klip A. Molecular mechanisms involved in GLUT4 translocation in muscle during insulin and contraction stimulation. In: Skeletal Muscle Metabolism in Exercise and Diabetes. Eds.: Richter EA, Kiens B, Galbo H, Saltin B. Plenum Press, Advances in Experimental Medicine and Biology, Vol. 441, 63-72, 1998.
Graham TE, Gibala MJ. Anaplerosis of the tricarboxylic acid cycle in human skeletal muscle during exercise: magnitude, sources, and potential physiological significance. In: Skeletal Muscle Metabolism in Exercise and Diabetes. Eds.: Richter EA, Kiens B, Galbo H, Saltin B. Plenum Press, Advances in Experimental Medicine and Biology, Vol. 441, 271-286, 1998.
Helge JW, Kriketos AD, Storlien LH. Insulin sensitivity, muscle fibre types, and membrane lipids. In: Skeletal Muscle Metabolism in Exercise and Diabetes. Eds.: Richter EA, Kiens B, Galbo H, Saltin B. Plenum Press, Advances in Experimental Medicine and Biology, Vol. 441, 129-138, 1998.
Helge JW, Storlien LH. Muscle membranes, Diet, and Exercise. In: "Biochemistry of Exercise X". Eds.: Hargreaves M, Thompson M. Human Kinetics Publ., Champaign Ill., 57-68, 1998.
Hespel P, Richter EA. Role of adenosine in regulation of carbohydrate metabolism in contracting muscle. In: Skeletal Muscle Metabolism in Exercise and Diabetes. Eds.: Richter EA, Kiens B, Galbo H, Saltin B. Plenum Press, Advances in Experimental Medicine and Biology, Vol. 441, 97-106, 1998.
Hundal HS, Darakhshan F, Kristiansen S, Blakemore SJ, Richter EA. GLUT5 expression and fructose transport in human skeletal muscle. In: Skeletal Muscle Metabolism in Exercise and Diabetes. Eds.: Richter EA, Kiens B, Galbo H, Saltin B. Plenum Press, Advances in Experimental Medicine and Biology, Vol. 441, 35-46, 1998.
Kiens B. Training and fatty acid metabolism. In: Skeletal Muscle Metabolism in Exercise and Diabetes. Eds.: Richter EA, Kiens B, Galbo H, Saltin B. Plenum Press, Advances in Experimental Medicine and Biology, Vol. 441, 229-238, 1998.
Kjær M. Adrenal medulla and exercise training. Eur J Appl Physiol 77, 195-199, 1998.
Kjær M. Hepatic glucose production during exercise. In: Skeletal Muscle Metabolism in Exercise and Diabetes. Eds.: Richter EA, Kiens B, Galbo H, Saltin B. Plenum Press, Advances in Experimental Medicine and Biology, Vol. 441, 117-128, 1998.
Kjær M. Hormonal response to exercise with acute hypoxia. In: "Progress in Mountain Medicine and High Altitude Physiology". Eds.: Ohno H, Kobayashi T, Masuyama S, Nakashima M. Dogura & Co. Kyoto. 255-277, 1998.
Kjær M. Neuroendocrine regulation during exercise. In: "Biochemistry of Exercise X". Eds.: Hargreaves M, Thompson M. Human Kinetics Publ., Champaign Ill., 47-56, 1998.
Kjær M, Galbo H. Work capacity, metabolism and hepatosplanchnic blood flow responses to exercise in liver-transplanted patients. In: Work capacity in organ transplantation. Rieu M (ed.). Med Sport Sci., Basel, Karger, 42, pp 134-140, 1998.
Langfort J, Ploug T, Ihlemann J, Enevoldsen LH, Stallknecht B, Saldo M, Kjær M, Holm, C, Galbo H. Hormone-sensitive lipase (HSL) expression and regulation in skeletal muscle. In: Skeletal Muscle Metabolism in Exercise and Diabetes. Eds.: Richter EA, Kiens B, Galbo H, Saltin B. Plenum Press, Advances in Experimental Medicine and Biology, Vol. 441, 219-228, 1998.
Ploug T, Ralston E. Anatomy of glucose transporters in skeletal muscle: effects of insulin and contractions. In: Skeletal Muscle Metabolism in Exercise and Diabetes. Eds.: Richter EA, Kiens B, Galbo H, Saltin B. Plenum Press, Advances in Experimental Medicine and Biology, Vol. 441, 17-26, 1998.
Ralston E, Ploug T. Pre-embedding staining of single muscle fibres for LM and EM studies of subcellular organization. In: The Science of Biological Specimen Preparation for Microscopy. Scanning Microscopy Suppl 10, 249-260, 1998.
Richter EA, Kiens B, Galbo H, Saltin B (Eds.) Skeletal Muscle Metabolism in Exercise and Diabetes. Plenum Press, Advances in Experimental Medicine and Biology, Vol. 441, 1998.
Richter EA, Kristiansen S, Wojtaszewski JFP, Daugaard JR, Asp S, Hespel P, Kiens B. Training effects on muscle glucose transport during exercise. In: Skeletal Muscle Metabolism in Exercise and Diabetes. Eds.: Richter EA, Kiens B, Galbo H, Saltin B. Plenum Press, Advances in Experimental Medicine and Biology, Vol. 441, 107-116, 1998.
Richter EA, Kristiansen S, Wojtaszewski JFP, Hundal H. Glucose transport and transporters in skeletal muscle. In: "Biochemistry of Exercise X". Eds.: Hargreaves M, Thompson M. Human Kinetics Publ., Champaign Ill., 169-184, 1998.
Stallknecht B, Vissing J, Galbo H. Lactate production and clearance in exercise. Effects of training. A mini-review. Scand J Med Sci Sports 8, 127-131, 1998.
Wojtaszewski JFP, Richter EA. Glucose utilization during exercise: Influence of endurance training. Acta Physiol Scand 162, 351-358, 1998.
II. Metabolism
II.b. Nucleotides, ammonia metabolism, glycogenolysis, K+ and pH regulation
Theses
Defended
Ph.D. thesis: Elsner P. The systematics of glycogen metabolism in myotubes; Cell cultures as in vitro model for investigations of glycogen metabolism. The Faculty of Health Sciences, University of Copenhagen. Defended August 1998.
Doctoral thesis: Hall Gv. Amino acids, ammonia and exercise in man. Maastricht, Rijksuniversiteit Limburg, 1996.
Doctor of Science thesis: Juel C. Lactate/proton co-transport in skeletal muscle. Faculty of Science, University of Copenhagen. Defended October 1997.
Ph.D. thesis: Nielsen PF. Glycolysis and gluconeogenesis in skeletal muscle. The Faculty of Health Sciences, University of Copenhagen. Defended June 1998.
Ph.D. thesis: Pilegaard H. Lactate transport in skeletal muscle - with special reference to muscle activity and blood flow. August Krogh Institute, University of Copenhagen, 1995.
Ph.D. thesis: Ratkevicius A. Low frequency fatigue of human skeletal muscle in isometric exercise. Lithuanian Institute of Physical Education, Medical Academy of Kaunas, Lithuania, 1996.
Ph.D. thesis: Wibrand F. Isolation and characterization of the skeletal muscle lactate/H+ cotransporter. August Krogh Institute, University of Copenhagen, 1996.
Original articles
1994
Bangsbo J, Graham T, Johansen L, Saltin B. Muscle lactate metabolism in recovery from intense, exhaustive exercise; impact of light exercise. J Appl Physiol 77, 1890-1895, 1994.
Juel C, Kristiansen S, Pilegaard H, Wojtaszewski J, Richter EA. Kinetics of lactate trancport in sarcolemmal giant vesicles obtained from human skeletal muscle. J Appl Physiol 76, 1031-1036, 1994.
MacLean DA, Graham TE, Saltin B.Branched chain amino acids augment ammonia metabolism while attenuating protein breakdown during exercise. Am J Physiol 267, E1010-E1022, 1994.
Mizuno M, Horn A, Secher NH, Quistorff B. Exercise-induced. 31P-NMR metabolic response of human wrist flexor muscles during partial neuromuscular blockade. Am J Physiol 267, R408-R414, 1994.
Mizuno M, Secher NH, Quistorff B. 31P-NMR spectroscopy, rsEMG, and histochemical fiber types of human wrist flexor muscles. J Appl Physiol 76, 531-538, 1994.
Pilegaard H, Bangsbo J, Richter EA, Juel C. Lactate transport studied in sarcolemmal giant vesicles from human muscle biopsies: relation to training status. J Appl Physiol 77, 1858-1862, 1994.
Sullivan MJ, Saltin B, Negro-Vilar R, Duscha BD, Charles HC. Skeletal muscle pH assessed by biochemical and 31P-MRS methods during exercise and recovery in man. J Appl Physiol 77, 2194-2200, 1994.
Wibrand F, Juel C. Reconstitution of the lactate carrier from rat skeletal-muscle sarcolemma. Biochem J 299, 533-537, 1994.
1995
Bangsbo J, Aagaard T, Olsen M, Kiens B, Turcotte LP, Richter EA. Lactate and H+ uptake in inactive muscles during intense exercise in man. J Physiol 488, 219-229, 1995.
Graham TE, Turcotte LP, Kiens B, Richter EA. Training and muscle ammonia and amino acid metabolism in humans during prolonged exercise. J Appl Physiol 78, 725-735, 1995.
Hall Gv, Saltin B, Vusse GJvd, Söderlund K, Wagenmakers AJM. Deamination of amino acids as a source for ammonia production during prolonged exercise. J Physiol 489, 251-266, 1995.
Juel C. Regulation of cellular pH in skeletal muscle fiber types, studied with sarcolemmal giant vesicles obtained from rat muscles. Biochim Biophys Acta 1265, 127-132, 1995.
Pilegaard H, Bangsbo J, Henningsen P, Juel C, Richter EA. Effect of blood flow on muscle lactate release studied in perfused rat hindlimb. Am J Physiol 269, E1044-E1051, 1995.
Pilegaard H, Juel C. Lactate transport studied in sarcolemmal giant vesicles from rat skeletal muscle: effect of denervation. Am J Physiol 269, E679-E682, 1995.
Ratkevicius A, Skurvydas A, Lexell J. Submaximal exercise induced impairment of human muscle to develop and maintain force at low frequence of electrical stimulation. Eur J Physiol 70, 294-300, 1995.
Tullson PC, Bangsbo J, Hellsten Y, Richter EA. IMP metabolism in human skeletal muscle after exhaustive exercise. J Appl Physiol 78, 146-152, 1995.
1996
Bangsbo J, Kiens B, Richter EA. Ammonia uptake in inactive muscles during exercise in humans. Am J Physiol 270, E101-E106, 1996.
Bangsbo J, Madsen K, Kiens B, Richter EA. Effect of muscle acidity on muscle metabolism and fatigue during intense exercise in man. J Physiol 495, 587-596, 1996.
Hellsten Y, Apple FS, and Sjödin B. The effect of sprint cycle training on scavenger enzymes in human skeletal muscle. J Appl Physiol 81, 1484-148, 1996.
Hellsten Y, Hansson H-A, Johnson L, Frandsen U, Sjödin B: Increased expression of xanthine oxidase and insulin-like growth factor (IGF-I) immunoreactivity in skeletal muscle after strenous exercise in humans. Acta Physiol Scand 157, 191-197, 1996.
Juel C. Symmetry and pH dependency of the lactate/proton carrier in skeletal muscle studied with rat sarcolemmal giant vesicles. Biochim Biophys Acta 1283, 106-110, 1996.
MacLean DA, Graham TE, Saltin B. Stimulation of muscle ammonia production during exercise following branched-chain amino acid supplementation in humans. J Physiol, 493, 909-922, 1996.
McCullagh KJA, Juel C, O'Brien M, Bonen A. Chronic muscle stimulation increases lactate transport in rat skeletal muscle. Mol Cell Biochem 156, 51-57, 1996.
1997
Bangsbo J, Juel C, Hellsten Y, Saltin B. Dissociation between lactate and proton exchange in muscle during intense exercise in man. J Physiol 504, 489-499, 1997.
Hellsten Y, Frandsen U, Ørthenblad N, Sjödin B, and Richter E. Xanthine oxidase in human skeletal muscle following eccentric exercise: A role in inflammation. J Physiol, 498, 239-248, 1997.
Hellsten Y, Tullson PC, Richter EA, Bangsbo J. Oxidation of urate in human skeletal muscle during exercise. Free Rad Biol Med 22, 169-174, 1997.
Ntziachristos V, Kreis R, Boesch C, Quistorff B. Dipolar resonance frequency shifts in 1H-MR spectra of skeletal muscle: confirmation in rats at 4.7T in-vivo and observations of changes post mortem. Magn Res Med 38, 33-39, 1997.
1998
Haller RG, Clausen T, Vissing J. Reduced levels of skeletal muscle Na+-K+-ATPase in McArdle disease. Neurology 50, 37-40, 1998.
Hamaoka T, Mizuno M, Osada T, Ratkevicius A, Nielsen AN, Nakagawa Y, Katsumuka T, Shimomitsu T, Quistorff B. Changes in oxygenation and phosphocreatine during exercise and recovery in relation to fiber types and capillary supply in human skeletal muscle. SPIE 3194, 478-484, 1998.
Hellsten Y, Sjödin B, Richter E, and Bangsbo J. Urate uptake and lowered ATP levels in human muscle after high-intensity intermittent exercise. Am J Physiol 274, E600-E606, 1998.
Juel C. Skeletal muscle Na+/H+ exchange in rats: pH dependency and the effect of training. Acta Physiol Scand 164, 135-140, 1998.
Juel C, Pilegaard H. Lactate/H+ transport kinetics in rat skeletal muscle related to fibre type and changes in transport capacity. Pflügers Arch - Eur J Physiol 436, 560-564, 1998.
Pilegaard H, Asp S. Effect of prior eccentric contractions on lactate/H+ transport in rat skeletal muscle. Am J Physiol 274, E554-E559, 1998.
Pilegaard H, Mohr T, Kjær M, Juel C. Lactate/H+ transport in skeletal muscle from spinal-cord-injured patients. Scand J Med Sci Sports 8, 98-101, 1998.
Søgaard K, Christensen H, Fallentin N, Mizuno M, Quistorff B, Sjøgaard G. Motor unit activation patterns during concentric wrist flexion in humans with different muscle fibre composition. Eur J Appl Physiol 78, 411-416, 1998.
Wilson MC, Jackson VN, Heddle C, Price NT, Pilegaard H, Juel C, Bonen A,
Montgomery I, Hutter OF, Halestrap AP. Lactic acid efflux from white skeletal muscle is catalyzed by the monocarbozylate transporter isoform MCT3. J Biol Chem 273, 15920-15926, 1998.
Reviews, Book chapters, Symposia contributions, etc.
1994
Hellsten Y. The role of zanthine oxidase in exercise. In: Exercise and oxygen toxicity. Eds: Sen CK, Packer L, Hänninen O. Elsevier Science Publishers, Amsterdam, 211-234, 1994.
1995
Graham TE, Rush JWE, MacLean DA: Skeletal muscle amino acid metabolism and
ammonia production during exercise. In: Hargreaves M (ed), Exercise Metabolism. Human Kinetics Pulishers, pp 131-175, 1995.
1996
Bangsbo J. Efficiency in repeated high intensity exercise. In: Muscular function in exercise and training with special references to human locomotion. Eds: Marconnet P, Saltin B, Komi PV, Poortsmans J. Basel, Karger, 21-31, 1996.
Bangsbo J. Regulation of muscle glycogenolysis and glycolysis during intense exercise - in vivo studies using repeated intense exercise. In: Biochemistry of Exercise IX. Eds: Maughan R, Shirreffs S. Human Kinetics Publ., 261-275, 1996.
Hellsten Y. Adenine nucleotide degradation: a role in free radical generation and protection. In: Muscular function in exercise and training with special reference to human locomotion. Eds: Marconnet P, Saltin B, Komi P, Poortmans J. Karger, Basel, 102-120, 1996.
Juel C. Lactate/proton co-transport in skeletal muscle: regulation and importance for pH homeostasis. Acta Physiol Scand 156, 369-374, 1996.
1997
Graham TE, Turcotte LP, Kiens B, Richter EA. Effect of endurance training on ammonia and amino acid metabolism in humans. Med Sci Sports Exerc 29, 646-653, 1997.
Juel C. Lactate/proton co-transport in skeletal muscle. Physiological Reviews 77, 321-358, 1997.
1998
Bangsbo J. Quantification of anaerobic energy production during intense exercise. Med Sci Sports Exerc 30, 47-52, 1998.
Bangsbo J, Krustrup P, Gonzalez-Alonso J, Saltin B. Energetics and efficiency of human skeletal muscle. In: "Motor Efficiency from Muscle to Man". Eds.: Abbate F, Gerrits HG, Houdijk H, Jansen C, Verheyen R. Printpartners Ipskamp, Enschede. 35-40, 1998.
Graham TE, MacLean DA. Ammonia and amino acid metabolism in skeletal muscle: human, rodent and canine models. Med Sci Sports Exerc 30, 34-46, 1998.
Juel C. Muscle pH regulation; role of training. Acta Physiol Scand 162, 359-366, 1998.
Juel C, Pilegaard H. Lactate exchange and pH regulation in skeletal muscle. In: "Biochemistry of Exercise X". Eds.: Hargreaves M, Thompson M. Human Kinetics Publ., Champaign Ill., 185-200, 1998.
II. Metabolism
II.c. Amino acids andImmune response
Thesis
Ph.D. thesis: Rohde, T. Exercise, Glutamine and The Immune System. The Faculty of Health Sciences, University of Copenhagen. Defended May 1998.
Original articles
1994
Kappel M, Kharazmi A, Nielsen H, Gyhrs A, Pedersen BK. Modulation of the counts and functions of neutrophils and monocytes under in vivo hyperthermia conditions. Int J Hyperthermia 10, 165-173, 1994.
Kappel M, Hansen MB, Diamant M, Pedersen BK. In vitro effects of human growth hormone on the proliferative responses and cytokine production of blood mononuclear cells. Hormone Metab Res 26, 612-612, 1994.
Tvede N, Kappel M, Klarlund K, Duhn S, Halkjær Kristensen J, Kjær M, Galbo H, Pedersen BK. Evidence that the effect of bicycle exercise on blood mononuclear cell proliferative responses and subsets is mediated by epinephrine. Int J Sports Med 15, 100-104, 1994.
Ullum H, Haahr PM, Diamant M, Palmø J, Halkjær-Kristensen J, Pedersen BK. Bicycle exercise enhances plasma-IL-6, but do not change pre-mRNA for IL-1a , IL-1ß, IL-6 or TNF-a in blood mononuclear cells. J Appl Physiol 77, 93-7, 1994.
1995
Hoffman-Goetz, Pedersen BK. (letter) Immunology Today 16(3), p.165, 1995.
Kappel M, Barington T, Gyhrs A, Pedersen BK. Influence of elevated body temperature on circulating immunoglobulin-secreting cells. Int J Hyperthermia 10, 653-658, 1995.
Kappel M, Tvede N, Hansen MB, Stadeager C, Pedersen BK. Cytokine production ex vivo: Effect of raised body temperature. Int J Hyperthermia 11, 329-335, 1995.
Klokker M, Kjær M, Secher NH, Hanel B, Worm L, Kappel M, Pedersen BK. Natural killer cell response to exercise in humans: effect of hypoxia and epidural anesthesia.
J Appl Physiol 78, 709-16, 1995.
Palmø J, Asp S, Daugaard J, Richter E, Pedersen BK. Effect of eccentric exercise on natural killer cell activity. J Appl Physiol 78, 1442-6, 1995.
Rohde T, Ullum H, Rasmussen JP, Halkjær Kristensen J, Newsholme E, Pedersen BK. Effects of glutamine on the immune system: influence of muscular exercise and HIV infection. J Appl Physiol 79, 146-150, 1995.
1996
Nielsen HB, Secher NH, Christensen NJ, Pedersen BK. Lymphocytes and NK cell activity during repeated bouts of maximal exercise. Am J Physiol 271, R222-R227, 1996.
Nielsen HB, Secher NH, Kappel M, Hanel B, Pedersen BK. Lymphocyte, NK, and LAK cell responses to maximal exercise. Int J Sports Med 17, 60-65, 1996.
Rohde T, MacLean DA, Hartkopp A, Pedersen BK. The immune system and serum glutamine during a triathlon. Eur J Appl Physiol 74, 428-434, 1996.
Rohde T, Maclean D, Pedersen BK. Glutamine, lymphocyte proliferation and cytokine production. Scand J Immunology 44, 648-650, 1996.
1997
Bruunsgaard H, Galbo H, Halkjær Kristensen J, Johansen TL, MacLean DA, Pedersen BK. Exercise-induced increase in interleukin-6 in humans is related to muscle damage. J Physiol (Lond) 499, 833-841, 1997.
Bruunsgaard H, Hartkopp A, Mohr T, Konradsen H, Heron I, Mordhorst CH, Pedersen BK. In vivo cell-mediated immunity and vaccination response following prolonged, intense,
exercise. Med Sci Sports Exerc 29(9), 1176-1181, 1997.
Kappel M, Gyhrs A, Galbo H, Pedersen BK. The response on glucoregulatory hormones of in vivo whole body hyperthermia. Int J Hyperthermia 13 (4), 413-421, 1997.
Klokker M, Secher NH, Olesen HL, Madsen P, Warberg J, Pedersen BK. Adrenergic beta-1 and beta-1+2 receptor blockade suppress the natural killer cell response to head-up tilt in humans. J Appl Physiol 83(5), 1492-1498, 1997.
Nielsen HB, Pedersen BK. Lymphocyte proliferation in response to exercise. Eur J Appl Physiol 75, 373-379, 1997.
Nielsen HB, Secher NH, Kristensen JH, Christensen NJ, Espersen K, Pedersen BK. Splenectomy impairs lymphocytosis during maximal exercise. Am J Physiol 272, R1847-R1852, 1997.
Rohde T, MacLean DA, Richter EA, Kiens B, Pedersen BK. Prolonged submaximal eccentric exercise is associated with increased levels of plasma IL-6. Am J Physiol 273, E85-E91, 1997.
1998
Kappel M, Dela F, Barington T, Galbo H, Pedersen BK. Immunological effects of a hyperinsulinemic euglycemic insulin clamp in healthy males. Scan J Immunology 47, 363-368, 1998.
Kappel M, Poulsen TD, Galbo H, Pedersen BK. Effect of elevated plasma noradrenaline concentration on the immune system in humans. Eur J Appl Physiol 79, 93-98, 1998.
Kappel M, Poulsen T, Galbo H, Pedersen BK. The influence of minor increases in plasma catecholamines on the natural killer cell activity. Hormone Res 49, 22-26, 1998.
Kappel M, Poulsen T, Hansen M, Galbo H, Pedersen BK. Somastatin attenuates the hyperthermia induced increase in neutrophil function. Eur J Appl Physiol 77, 149-156, 1998.
Klokker M, Mohr T, Kjær M, Galbo H, Pedersen BK. The natural killer cell reponse to exercise in spinal cord injured individuals. Eur J Appl Physiol 79, 106-109, 1998.
Nielsen HB, Secher NH, Kappel M, Pedersen BK. N-acetylcysteine does not affect the lymphocyte proliferation and natural killer cell activity responses to exercise. Am J Physiol 275, R1227-R1231, 1998.
Ostrowski K, Hermann C, Bangash A, Schjerling P, Nielsen JN, Pedersen BK. A trauma-like elevation of plasma cytokines in humans in response to treadmill running. J Physiol 513, 889-894, 1998.
Ostrowski K, Rohde T, Zacho M, Asp S, Pedersen BK. Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running. J Physiol 508, 949-953, 1998.
Rohde T, Asp S, MacLean SA, Pedersen BK. Competitive sustained exercise in humans, lymphokine activated killer cell activity, and glutamine - an intervention study. Eur J Appl Physiol 78, 448-453, 1998.
Rohde T, MacLean DA, Pedersen BK. Effect of glutamine supplementation on changes in the immune system induced by repeated exercise. Med Sci Sports Exerc 30(6), 856-862, 1998.
Reviews, Book chapters, Symposia contributions, etc.
1994
Hoffman-Goetz, Pedersen BK. Exercise and the immune system. A model of the stress response? Immunology Today 15, 345-392, 1994.
Pedersen BK, Ullum H. NK cell response to physical activity -possible mechanisms of action. Med Sci Sports Exerc 26, 140,146, 1994.
1995
Pedersen BK, Bruunsgaard H. How physical exercise influences the establishment of infections. Review Article. Sports Medicine, Adis International 19(6), 393-400, 1995.
1996
Brines R, Hoffman-Goetz L, Pedersen BK. Can you exercise to make your immune system
fitter? Immunology Today 17, 252-254, 1996.
Pedersen BK. Immune responses to acute exercise. In: Exercise and the Immune Response. Ed. Hoffman-Goetz. CRC Press, 79-93, 1996.
Pedersen BK. Acute Time-limited Exercise Stress and The Immune System: Role of Stress Hormones. In: Biochemistry of Exercise. Eds. Maughan RJ, Shirreffs SM. Human Kinetics, Champaign, Ill, 358-363, 1996.
1997
Pedersen BK (Ed.). "Exercise-Immunology". BK. R.G.Landes Company, Medical Intelligence Unit, Biomedical Publishers, pp 1-206, 1997.
1998
Pedersen BK, Nieman DC. Exercise and Immunology: integration and regulation. Immunology Today 19(5), 204-205, 1998.
Pedersen BK, Ostrowski K, Rohde T, Bruunsgaard H. Nutrition, exercise and the immune system. Proc Nutrition Soc 57, 43-47, 1998.
Pedersen BK, Ostrowski K, Rohde T, Bruunsgaard H. Strenuous exercise - a model of the cytokine response to trauma and sepsis. Can J Physiol Pharmacol 76(5), 505-511, 1998.
Pedersen BK, Rohde T, Ostrowski K. Recovery of the immune system after exercise. Acta Physiol Scand 162, 325-332, 1998.
Rohde T, Krzywkowski K, Pedersen BK. Glutamine, exercise and the immune system - is there a link? Exerc Immun Rev 4, Human Kinetics Publ., Champaign, Ill., pp 49-63, 1998.
III. Cardiovascular and mitochondrial respiration
Theses
Defended
Doctoral thesis: Boushel R. The muscle metaboreflex. The Copenhagen Muscle Research Center, Rigshospitalet, Copenhagen, and Department of Health Sciences, Sargent College of Boston University, Boston, MA. Defended January 1998.
Doctoral thesis: Jørgensen LG. Transcraniel Doppler ultrasound for cerebral perfusion. Acta Physiol Scand 154, suppl. 625, 1995.
Ph.D. thesis: Koskolou M. Differential effects of low arterial oxygen tension and hemoglobin on skeletal muscle oxygen delivery and utilization during exercise in humans. The Faculty of Science, University of Copenhagen, Defended April 1998.
Doctoral thesis: Vissing SF. Differential activation of sympathetic discharge to skin and skeletal muscle in humans. Acta Physiol Scand 161 (suppl 639): 1-32, 1997.
Submitted:
Doctoral thesis: Pott FC. Regulation of cerebral perfusion during exercise". Faculty of Health Science, University of Copenhagen, will be submitted ??, 1997.
Ph.D. thesis: Rådegran G. Leg blood flow at transition from rest to exercise; Ultrasound Doppler estimates". Faculty of Health Sciences, University of Copenhagen, will be submitted, March 1998.
Original articles
1994
Kjær M, Perko G, Secher NH, Boushel R, Beyer N, Pollack S, Horn A, Fernandez A, Mohr T, Lewis SF, Galbo H. Cardiovascular and ventilatory responses to electrically induced cycling with complete epidural anaesthesia in humans. Acta Physiol Scand 151, 199-207, 1994.
Ray CA, Secher NH, Mark AL. Modulation of sympathetic nerve activity during posthandgrip muscle ischemia in man. Am J Physiol 266, H79-H83, 1994.
Vissing SF, Scherrer U, Victor RG. Increase of sympathetic discharge to skeletal muscle but not to skin during mild lower body negative pressure in humans. J Physiol 481: 233-241, 1994.
Williamson JW, Mitchell JH, Olesen HL, Raven P, Secher NH. Reflex increase in blood pressure by leg compression in man. J Physiol 475, 351-357, 1994.
1995
Kim CK, Bangsbo J, Strange S, Saltin B. Skeletal muscle perfusion in electrically induced dynamic exercise in humans. Acta Physiol Scand 153, 279-287, 1995.
Linkis P, Jørgensen LG, Olesen HP, Madsen PL, Lassen NA, Secher NH. Dynamic exercise enchances regional cerebral artery mean flow velocity. J Appl Physiol 78, 12-16. 1995.
Olesen HL, Mitchell JH, Friedman DB, Iversen HK, Secher NH. Reduced arterial diameters during static exercise in man. Acta Physiol Scand 153, 335-341, 1995.
Savard GK, Areskog NH, Saltin B: Cardiovascular response to exercise in humans following acclimatization to extreme altitude. Acta Physiol Scand 154: 499-509, 1995.
Victor RG, Secher NH, Lyson T, Mitchell JH. Central command increases muscle sympathetic nerve activity during intense intermittent isometric exercise in humans. Circ Res 76, 127-131, 1995.
1996
Frandsen U, Lopez-Figueroa M, Hellsten Y: Localization of nitric oxide synthase in human skeletal muscle. Biochem Biophys Res Com 227, 88-93. 1996.
Hallén J, Saltin B, Sejersted OM. K+ balance during exercise and role of b-adrenergic stimulation. Am J Physiol 270, R1347-54, 1996.
Perko MJ, Perko G, Just S, Secher NH, Schoeder TV. Changes in superior mesenteric artery Doppler waveform during reduction of cardiac stroke volume and hypertension. Ultrasound Med Biol 22, 11-18, 1996.
Pott F, Jensen K, Hansen H, Christensen NJ, Lassen NA, Secher NH. Middle cerebral artery blood velocity and plasma catecholamines during exercise. Acta Physiol Scand 158, 349-356, 1996.
Williamson JW, Friedman DB, Mitchell JH, Secher NH, Friberg L. Mechanisms regulating regional cerebral activation during dynamic handgrip in humans. J Appl Physiol 81, 1884-1890, 1996.
Williamson JW, Olesen HL, Pott F, Mitchell JH, Secher NH. Central command increases cardiac output during static exercise in humans. Acta Physiol Scand 156, 429-434, 1996.
Vissing SF, Hjortsø EM. Central motor command activates sympathetic outflow to the cutaneous circulation in humans. J Physiol 492, 931-939, 1996
1997
Blomstrand E, Rådegran G, Saltin B. Maximum rate of oxygen uptake by human skeletal muscle in relation to maximal activities of enzymes in the Krebs cycle. J Physiol 501, 455-460, 1997.
Gibala MJ, MacLean DA, Graham T, Saltin B. Anaplerotic processes in human skeletal muscle during brief dynamic exercise. J Physiol 502, 703-713, 1997.
Hanel B, Teunissen I, Rabøl A, Warberg J,Secher NH. Restricted postexercise pulmonary diffusion capacity and central blood volume depletion. J Appl Physiol 83, 11-17, 1997.
Hellsten Y, Frandsen U. Adenosine formation in contracting primary rat skeletal muscle cells and endothelial cells in culture. J Physiol, 504-3, 695-704, 1997.
Koskolou M, Calbet JAL, Rådegran G, Roach RC. Hypoxia and the cardiovascular response to dynamic knee extensor exercise. Am J Physiol 272, H2655-2663, 1997.
Koskolou MD, Roach RC, Calbet JAL, Rådegran G, Saltin B. Cardiovascular responses to dynamic exercise with acute anemia in humans. Am J Physiol 273, H1787-H1793, 1997.
MacLean DA, Saltin B, Rådegran G, Sinoway L. Femoral arterial injection of adenosine in humans elevates MSNA via central but not peripheral mechanisms. J Appl Physiol 83, 1045-1053, 1997.
Pawelczyk JA, Pawelczyk R, Warberg J, Mitchell JH, Secher NH. Cardiovascular and catecholamine responses to static exercise in partially curarized humans. Acta Physiol Scand 160, 23-28, 1997.
Pott F, Knudsen L, Nowak M, Nielsen HB, Hanel B, Secher NH. Middle cerebral artery blood velocity during rowing. Acta Physiol Scand 160, 251-255, 1997.
Pott F, Ray CA, Olesen HL, Ide K, Secher NH. Middle cerebral artery blood velocity, arterial diameter and muscle sympathetic nerve activity during post-exercise muscle
ischaemia. Acta Physiol Scand 160, 43-47, 1997.
Rådegran G. Ultrasound Doppler estimates of femoral artery blood flow during dynamic knee extensor exercise in man. J Appl Physiol 83, 1383-1388, 1997.
Vissing SF, Secher NH, Victor RG. Mechanism of cutaneous vasoconstriction during upright posture. Acta Physiol Scand 159, 131-138, 1997.
1998
Boushel R, Ide K, Møller-Sørensen H, Fernandes A, Pott F, Secher NH. Nirs and indocyanine green determined muscle blood flow during exercise in humans. SPIE 3194, 145-150, 1998.
Boushel R, Madsen P, Nielsen HB, Quistorff B, Secher NH. Contribution of pH, diprotonated phosphate and potassium for the reflex increase in blood pressure during handgrip. Acta Physiol Scand 164, 269-275, 1998.
Boushel R, Pott F, Madsen P, Rådegran G, Nowak M, Quistorff B, Secher NH. Muscle metabolism from near infrared spectroscopy during rhythmic handgrip in humans. Eur J Appl Physiol 79, 41-48, 1998.
Gibala MJ, MacLean DA, Graham TE, Saltin B. Tricarboxylic acid cycle intermediate pool size and estimated cycle flux in human muscle during exercise. Am J Physiol 275, E235-E242, 1998.
Hellsten Y, MacLean DA, Rådegran G, Saltin B, Bangsbo J. Adenosine concentrations in the interstitium of resting and contracting human skeletal muscle. Circulation 98, 6-8, 1998.
Ide K, Pott F, Lieshout JJv, Secher NH. Middle cerebral artery blood velocity depends on cardiac output during exercise with a large muscle mass. Acta Physiol Scand 162, 13-20, 1998.
Langberg H, Bülow J, Kjær M. Blood flow in the peritendinous space of the human Achilles tendon during exercise. Acta Physiol Scand 163, 149-153, 1998.
MacLean DA, Vissing J, Vissing S, Haller RG. Oral branched chain amino acids do not improve exercise capacity in McArdle disease. Neurology 51, 1456-1459, 1998.
Nielsen HB, Madsen P, Svendsen LB, Roach RC, Secher NH. The influence of PaO2, pH and SaO2 on maximal oxygen uptake. Acta Physiol Scand 164, 89-97, 1998.
Perko MJ, Nielsen HB, Skak C, Clemmesen JO, Schroeder TV, Secher NH. Mesenteric, coeliac, and splanchnic blood flow in humans during exercise. J Physiol 513, 907-913, 1998.
Rådegran G, Pilegaard H, Nielsen JJ, Bangsbo J. Microdialysis ethanol removal reflects probe recovery rather than local blood flow in skeleetal muscle. J Appl Physiol 85, 751-757, 1998.
Rådegran G, Saltin B. Muscle blood flow at onset of dynamic exercise in humans. Am J Physiol 274, H314-H322, 1998.
Vissing J, Vissing S, MacLean DA, Saltin B, Quistorff B, Haller RG. Sympathetic activation in exercise is not dependent on muscle acidosis. Direct evidence from studies in metabolic myopathies. J Clin Invest 101, 1654-1660, 1998.
Reviews, Book Chapters, Symposia Contributions, etc.
1994
Bundgaard H, Schmidt TA, Olesen HL, Secher NH, Kjeldsen K. Digoxin induced dysfunction of skeletal muscle potassium homostasis during exercise. In: The Sodium Pump. Eds: Bamberg E, Schoner W. Springer New York, 840-843, 1994.
Secher NH, Ray CA. Heart reflexes in adjustment to dynamic exercise. In: International Society for Heart Research, XV European Section Meeting. Haunsø S, Kjeldsen K (eds.). Monduzzi Editore, Bologna, Italy, 189-197, 1994.
Secher NH, Saltin B. Modulation of metabolic vasodilatation during dynamic exercise in man. J Exerc Sci 4, 1-10, 1994.
1997
Bangsbo J. Physiology of muscle fatigue during intense exercise. In: The clinical pharmacology of sport and exercise. Reilly T, Orme M (eds.) Elvier Science BV, 123-130, 1997.
Saltin B. Blood flow and substrate exchange in skeletal muscle of man: techniques relevant for use in the study of the ageing process of muscle. Muscle & Nerve, suppl. 5, S107-S109, 1997.
Saltin B, Magnusson G. The chronic heart failure patient: a role for exercise training. Excerpta Medica, Everyday Problems in Clinical Cardiology 6 (9), 3-11, 1997.
Secher NH, Nielsen HB, Madsen P. Fluid volume homeostasis: acute effects of exercise and adaptation to training. Österreichische Gesellschaft für Klinische Chemie, Sonderhaft, 27-29, 1997.
Secher NH, Saltin B. Blood flow regulation during exercise in man. In: The Physiology and Pathophysiology of Exercise Tolerance. Eds: Ward SA, Steinacker J. London, Plenum Press, pp. 97-102, 1997.
Wagner PD, Hoppeler H, Saltin B. Determinants of maximal oxygen uptake. In: The Lung.Crystal RG, West JB, Weibel ER, Barnes PJ (eds). Scientific Foundations, 2nd edition. Lippincott-Raven Publ., Philadelphia, pp. 2033-2041, 1997.
1998
Bangsbo B, Hellsten Y. Muscle blood flow and oxygen uptake in recovery from exercise. Acta Physiol Scand 162, 305-312, 1998.
Richardson RS, Saltin B: Human muscle blood flow and metabolism studied in the isolated quadriceps muscles. Med Sci Sports Exerc 30(1), 28-33, 1998.
Saltin B, Rådegran G, Koskolou MD, Roach RC. Skeletal muscle blood flow in humans and its regulation during exercise. Acta Physiol Scand 162, 421-436, 1998.